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Pharmacological treatments for heart damage brought on by COVID-19

Nicola Ward, Geoff Smith

The 2019 Coronavirus Illness (COVID-19), a current global pandemic that started in March 2020, is caused by SARS-CoV-2. About 935,000 people have died as a result of COVID-19 so far, across more than 200 nations. Injuries brought on by COVID-19 primarily impact the respiratory system, but they can also damage other organs, such as the cardiovascular system. The Angiotensin 2 Conversion Enzyme allows SARS-CoV-2 to enter host cells (ACE-2). ACE-2 is expressed in various organs, including the cardiovascular system, in addition to the lungs. A significant number of individuals with severe COVID-19 have cardiac abnormalities, such as myocardial fibrosis, edema, and pericarditis, according to several studies. Myocardial fibrotic lesions are brought on by the pathological remodeling of the extracellular matrix brought on by viral infection.

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