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Modern developments in the ampicillin medicinal chemistry

Daniel Pack, Chris Delcher

The Antibiotic Ampicillin (AMP), which belongs to the -lactam family, has a wide range of effects in both the prevention and treatment of different bacterial diseases. Antibiotic misuse has facilitated the spread of multidrug resistance in pathogenic strains. As a result, the biological activity of numerous crucial medications, including AMP, has been lost. The creation of new antibiotic drugs, their modification, and complexation with metal ions, which can enhance their biological properties, appear to be the research areas that currently have researchers' attention the most. Additionally, penicillin residues in food and the environment have drawn a lot of attention recently due to increased worries about food safety and public health.

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