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Isosexual peripheral precocious puberty in a girl: A rare presentation of Adrenocortical Carcinoma

Shiva Madan, Kul Ranjan Singh, Virendra Atam, Anand Mishra, Atin Singhai, and Neha Nagpal

Precocity puberty was defined as the appearance of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. precocity puberty can be due to GnRH-dependent or GnRH-independent causes. Childhood Adrenocortical Carcinoma (ACC), a rare cause of GnRH-independent precocious puberty, was hormonally active in >90% of cases. Childhood adrenal cortex cancer was aggressive childhood cancer. The tumors have a varied presentation either precocity/ virilization or presentation with Cushing’s syndrome or both.

协会、社团和大学的同行评审出版 pulsus-health-tech