Anatomical variations of inferior vena cava and its tributaries are not uncommon during abdominal and pelvic surgeries. Among the variations of inferior vena cava the infrarenal type is rare. During the routine dissection of a male cadaver, such rare variation in formation of inferior vena cava was found associated with agenesis of common iliac vein. Although they may not be of functional importance but knowledge of such variations is essential for surgical point of view. Some variations are common and some are rare. It becomes essential to find out their structural and functional importance in the body. Unfortunately, they are missed during preoperative assessment of patients even in the era of advanced radiological interventions unless they are hazardous or altered any function. Therefore, developmental origin of these variants gets equal attention.